
- exposure pathway: 迅速且完全吸收。
- Harmful effect: 罕见情况下,氟他胺与间质性肺炎相关,可能导致肺纤维化,约0.04%的患者会出现。
- Toxicity summary: 氟他胺是一种非甾体抗雄激素,通过与雄激素受体结合阻断内源性和外源性睾酮的作用。此外,氟他胺是睾酮刺激的前列腺DNA合成的强效抑制剂。而且,它能够抑制雄激素的前列腺核摄取。
- Regulatory information: 加州化妆品安全计划(CSCP)报告成分:报告 - 无论成分在产品中的预期功能如何
- Hepatotoxicity: 可能性评分:A(已知的明显肝损伤原因)。
- Symptoms and Signs: 单独使用氟他胺的动物研究中,过量的症状包括活动减少、竖毛、呼吸缓慢、共济失调和/或流泪、食欲不振、镇静、呕吐和高铁血红蛋白血症。
- Hazard categories and classifications: 对水生环境有害(长期)- 1类
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
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fluoro amine 98% 5/g
fluoro amine 98% 5/g Macklin 13311-84-7, available in complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials




