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Product introduction
Foretinib (GSK1363089)是一种ATP竞争性的HGFR和VEGFR抑制剂,作用于Met和KDR作用最强,IC50分别为0.4 nM和0.9 nM,对Ron, Flt-1/3/4, Kit, PDGFRα/β和Tie-2作用效果稍弱,对FGFR1和EGFR几乎没有抑制活性。An ATP-competitive inhibitor of tyrosine kinases including Flt-1, Flt-4, Met, and Ron. Foretinib (GSK1363089) is an ATP-competitive inhibitor of HGFR and VEGFR, mostly for Met and KDR with IC50 of 0.4 nM and 0.9 nM. Less potent against Ron, Flt-1/3/4, Kit, PDGFRα/β and Tie-2, and little activity to FGFR1 and EGFR An ATP-competitive inhibitor of tyrosine kinases including Flt-1, Flt-4, Met, and Ron.
Chinese name
Foretinib (GSK1363089),抑制剂, 血管内皮生长因子受体抑制剂
English name
Foretinib (GSK1363089)
Chinese alias
-
English alias
81FH7VK1C4 | Foretinib [USAN:INN] | N-(3-FLUORO-4-((6-METHOXY-7-(3-(MORPHOLIN-4-YL)PROPOXY)QUINOLIN-4-YL)OXY) PHENYL)-N'-(4-FLUOROPHENYL)CYCLOPROPANE-1,1-DICARBOXAMIDE | Foretinib | PB27007 | MLS006010302 | Foretinib (USAN/INN) | GSK 1363089 | NCGC0026310
CAS number
849217-64-7
molecular formula
C34H34F2N4O6
molecular weight
632.65 g/mol
Exact mass
-
PSA
111.000 Ų
Logp
5.5
Technical Documents
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Foretinib (GSK1363089) ≥98% 5mg

Foretinib (GSK1363089) ≥98% 5mg CAS 849217-64-7, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:F864618-5mg
Product model:5mg
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Lead Time:30days
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