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Product details
名称
β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE
英文名称
β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE
货号
G1372126-1mg
包装规格
1mg
储存温度
室温
运输条件
常规运输
产品介绍
β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE 是一种木耳素-葡糖苷缀合物,对β-葡萄糖醛酸酶预处理和未处理的癌细胞的体外抗增殖活性具有良好的选择性,IC50 值为5.7 nM - 9.7 nM。在 HCT-116 异种移植小鼠模型中具有较强的抗肿瘤作用,且无副作用。 β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE (compound 20) is auristatins-glucuronide conjugate. Antitumor agent-122 shows in vitro antiproliferative activities against β-glucuronidase pretreated and untreated cancer cells with an IC50 value of 5.7 nM - 9.7 nM. Antitumor agent-122 shows potent antitumor efficacy in HCT-116 xenograft mouse model without inducing side effects
Safety
「No Dangerous Attributes」
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β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE 1mg

β-Glucuronide-NB-bis[N(Me)-methyl ester]-MMAE 1mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 1mg.

item number:G1372126-1mg
Product model:1mg
level: 1mg
Lead Time:30days
sold 519 Items
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Specifications:

1mg

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