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Product details

名称

GLPG0492

分子类型

小分子

英文别名

英文名称

GLPG0492

货号

G646594-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

GLPG0492 is a non-steroidal selective androgen receptor modulator (potency 12 nM). GLPG0492 has the potential for the research of musculo-skeletal diseases such as sarcopenia and cachexia. Form:Solid

生化机理

GLPG0492 是一种非甾体选择性雄激素受体调节剂（效力为 12 nM）。GLPG0492 具有研究肌肉骨骼疾病（如肌肉疏松症和恶病质）的潜力。

CAS号

1215085-92-9

分子式

C19H14F3N3O3

分子量

389.33 g/mol

PubChem编号

59317190

Isomeric SMILES

CN1C(=O)N(C(=O)[C@@]1(CO)C2=CC=CC=C2)C3=CC(=C(C=C3)C#N)C(F)(F)F

IIUPAC Name

4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl]-2-(trifluoromethyl)benzonitrile

INCHI

1S/C19H14F3N3O3/c1-24-17(28)25(14-8-7-12(10-23)15(9-14)19(20,21)22)16(27)18(24,11-26)13-5-3-2-4-6-13/h2-9,26H,11H2,1H3/t18-/m1/s1

InChi Key

VAJGULUVTFDTAS-GOSISDBHSA-N

Smiles

CN1C(=O)N(C(=O)C1(CO)C2=CC=CC=C2)C3=CC(=C(C=C3)C#N)C(F)(F)F

PubChem CID

59317190

溶解性

DMSO : ≥ 50 mg/mL (128.43 mM)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

389.099 Da

单同位素质量Monoisotopic Mass

389.099 Da

拓扑极表面积Topological Polar Surface Area

84.600 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

683

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

2.9

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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