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Product details

名称

GK187

分子类型

小分子

英文别名

英文名称

GK187

货号

G647067-5mg

包装规格

5mg

浓度

≥98%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

GK187 is a potent and selective Group VIA calcium-independent phospholipase A 2 (GVIA iPLA 2 ) inhibitor with an X I (50) value of 0.0001. GK187 can be used for researching various neurological disorders [The X I (50) is the mole fraction of the inhibitor in the total substrate interface required to inhibit the enzyme by 50%.] Form:Liquid IC50& Target:X I (50): 0.0001 (GVIA iPLA 2 )

生化机理

GK187 是一种强效的选择性 VIA 族钙依赖性磷脂酶 A 2（GVIA iPLA 2）抑制剂，其 X I (50) 值为 0.0001。GK187 可用于研究各种神经系统疾病。[X I (50)指的是非吸入性磷脂酶 A 2（GVIA iPLA 2）的摩尔分数。

CAS号

1071001-50-7

分子式

C14H15F5O2

分子量

310.26 g/mol

PubChem编号

25060072

Isomeric SMILES

COC1=CC=C(C=C1)CCCCC(=O)C(C(F)(F)F)(F)F

IIUPAC Name

1,1,1,2,2-pentafluoro-7-(4-methoxyphenyl)heptan-3-one

INCHI

1S/C14H15F5O2/c1-21-11-8-6-10(7-9-11)4-2-3-5-12(20)13(15,16)14(17,18)19/h6-9H,2-5H2,1H3

InChi Key

CICDFDPOGZQTQB-UHFFFAOYSA-N

Smiles

COC1=CC=C(C=C1)CCCCC(=O)C(C(F)(F)F)(F)F

PubChem CID

25060072

溶解性

DMSO : 100 mg/mL (322.31 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

310.099 Da

单同位素质量Monoisotopic Mass

310.099 Da

拓扑极表面积Topological Polar Surface Area

26.300 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

333.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

4.500

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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