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Product details

名称

Garcinone D

分子类型

小分子

别名

加西诺内D

英文别名

英文名称

Garcinone D

货号

G651205-5mg

包装规格

5mg

浓度

≥98%

储存温度

避光,-80℃储存

运输条件

超低温冰袋运输

产品介绍

Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3) , Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2) , heme oxygenase-1 (HO-1) in concentration- and time- dependent manners Form:Solid IC50& Target:p-STAT3

生化机理

山竹果中的天然氧雜蔥酮能促進 C17.2 神經幹細胞的增殖。加西酮 D 能提高磷酸化信号转导和转录激活因子 3 (p-STAT3)、细胞周期蛋白 D1 和核因子 e 的蛋白水平。

CAS号

107390-08-9

分子式

C24H28O7

分子量

428.47 g/mol

PubChem编号

5495926

Isomeric SMILES

CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)OC)CCC(C)(C)O)O)C

IIUPAC Name

1,3,6-trihydroxy-8-(3-hydroxy-3-methylbutyl)-7-methoxy-2-(3-methylbut-2-enyl)xanthen-9-one

INCHI

1S/C24H28O7/c1-12(2)6-7-13-15(25)10-18-20(21(13)27)22(28)19-14(8-9-24(3,4)29)23(30-5)16(26)11-17(19)31-18/h6,10-11,25-27,29H,7-9H2,1-5H3

InChi Key

TYALNCRUIKOKGP-UHFFFAOYSA-N

Smiles

CC(=CCC1=C(C2=C(C=C1O)OC3=C(C2=O)C(=C(C(=C3)O)OC)CCC(C)(C)O)O)C

PubChem CID

5495926

溶解性

DMSO : 50 mg/mL (116.69 mM; Need ultrasonic)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

428.184 Da

单同位素质量Monoisotopic Mass

428.184 Da

拓扑极表面积Topological Polar Surface Area

116.000 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

671.000

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

XLogP3

4.900

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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