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Product details

名称

GSK-3 inhibitor 1

别名

GSK-3 抑制剂 1

英文名称

GSK-3 inhibitor 1

货号

G651337-5mg

包装规格

5mg

浓度

≥98%

储存温度

2-8°C储存,干燥

运输条件

冰袋运输

产品介绍

GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny) In Vitro GSK-3 inhibitor 1 can be used to induce, promote or enhance the growth, proliferation or regeneration of inner ear tissues such as inner ear supporting cells or inner ear hair cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:GSK-3

生化机理

GSK-3抑制剂1（化合物核心3）是一种GSK-3抑制剂，可诱导干细胞/祖细胞自我更新（例如，诱导干细胞/祖细胞增殖，同时保持后代分化成组织细胞的能力）。

CAS号

603272-51-1

分子式

C22H17ClFN5O2

分子量

437.85 g/mol

PubChem编号

78357782

Isomeric SMILES

C1CN2C=C(C3=CC(=CC(=C32)CN1)F)C4=C(C(=O)NC4=O)C5=CN=C6N5C=CC=C6.Cl

IIUPAC Name

3-(6-fluoro-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl)-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione;hydrochloride

INCHI

1S/C22H16FN5O2.ClH/c23-13-7-12-9-24-4-6-27-11-15(14(8-13)20(12)27)18-19(22(30)26-21(18)29)16-10-25-17-3-1-2-5-28(16)17;/h1-3,5,7-8,10-11,24H,4,6,9H2,(H,26,29,30);1H

InChi Key

CXXAOCQHGIGIBJ-UHFFFAOYSA-N

Smiles

C1CN2C=C(C3=CC(=CC(=C32)CN1)F)C4=C(C(=O)NC4=O)C5=CN=C6N5C=CC=C6.Cl

PubChem CID

78357782

溶解性

DMSO : 12.5 mg/mL (28.55 mM; ultrasonic and warming and heat to 60°C)

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

437.105 Da

单同位素质量Monoisotopic Mass

437.105 Da

拓扑极表面积Topological Polar Surface Area

80.400 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

787

同位素原子数Isotope Atom Count

共价键合单元计数Covalently-Bonded Unit Count

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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