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Product details

名称

GSK 690 Hydrochloride

别名

GSK 690 盐酸盐

英文名称

GSK 690 Hydrochloride

货号

G661638-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

GSK 690 (Hydrochloride) is a reversible inhibitor of lysine specific demethylase 1 (LSD1) , with a K d value of 9 nM and a biochemical IC 50 of 37 nM. IC50& Target:IC50: 37 nM (LSD1), Kd: 8 nM (LSD1) . In Vitro:GSK690 (1-10 μM) acts together with JNJ-26481585 to induce cell death in all four tested RMS cells lines (RD, RH30, RMS13, and TE381.T cells). GSK690/JNJ-26481585 cotreatment alters the balance between pro- and antiapoptotic proteins with 1 μM GSK690 Biological Activity:GSK 690 (Hydrochloride) is a reversible inhibitor of lysine specific demethylase 1 (LSD1) , with a K d value of 9 nM and a biochemical IC 50 of 37 nM.

分子式

C24H24ClN3O

分子量

405.92 g/mol

Smiles

N#CC1=CC=C(C2=CC(OC[C@H]3CNCC3)=CN=C2C4=CC=C(C)C=C4)C=C1.Cl

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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