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名称

Gemcitabine-O-Si(di-iso)-O-Mc

英文名称

Gemcitabine-O-Si(di-iso)-O-Mc

货号

G767857-1mg

包装规格

1mg

浓度

≥98%

储存温度

避光,-20°C储存

运输条件

超低温冰袋运输

敏感性

光敏感

产品介绍

Gemcitabine-O-Si(di-iso)-O-Mc 是抗体偶联活性分子的一部分，由嘧啶核苷类似物抗代谢药和抗肿瘤剂 Gemcitabine 和 ADC linker 连接而成。体外研究：抗体药物偶联物 (ADC) 通过在体循环中稳定但在靶细胞内裂解的接头将处理性单克隆抗体 (mAb) 与强效毒素偶联。 Gemcity-O-Si (di-iso) - O-Mc is a part of antibody conjugated active molecules, composed of pyrimidine nucleoside analogue antimetabolites and anti-tumor agents Gemcity-O-Si (di-iso) and ADC linker. In vitro studies: Antibody drug conjugates (ADCs) couple processing monoclonal antibodies (mAbs) with potent toxins through a linker that is stable in the systemic circulation but lyses within target cells.

生化机理

Gemcitabine-O-Si(di-iso)-O-Mc is a agent-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; linked via the ADC linker

分子式

C24H36F2N4O7Si

分子量

558.65 g/mol

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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