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Product introduction

Omipalisib (GSK2126458, GSK458)是一种高选择性的，有效的p110α/β/γ/δ和 mTORC1/2抑制剂，无细胞试验中Ki分别为0.019 nM/0.13 nM/0.024 nM/0.06 nM和0.18 nM/0.3 nM。Omipalisib 可诱导自噬。 GSK2126458 is a highly selective and potent inhibitor of PI3K with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM for p110α/β/δ/γ, mTORC1/2 , respectively.

Specs ⸢ View details ⸥

Chinese name

GSK2126458(GSK458),PI3激酶抑制剂, 雷帕霉素激酶机制靶点抑制剂

English name

GSK2126458 (GSK458)

Chinese alias

English alias

A25172 | CHEBI:95093 | HMS3656D09 | N-[2-Methoxy-5-[4-(4-pyridazinyl)-6-quinolinyl]-3-pyridinyl]benzenesulfonamide | D10718 | DTXSID10148604 | 2,4-difluoro-N-(2-(methyloxy)-5-(4-(4-pyridazinyl)-6-quinolinyl)-3-pyridinyl)benzenesulfonamide | GSK2126458 | G

CAS number

1086062-66-9

molecular formula

C25H17F2N5O3S

molecular weight

505.5 g/mol

Exact mass

PSA

115.000 Å²

Logp

3.3

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2, 4-difluoro-n-[2-methoxy-5-[4-(4-pyrazine)-6-quinoline]-3-pyridine]benzenesulfonylamine 10mM in DMSO 1ml

Name: 2, 4-difluoro-n-[2-methoxy-5-[4-(4-pyrazine)-6-quinoline]-3-pyridine]benzenesulfonylamine 10mM in DMSO 1ml
Brand: 麦克林
SKU: G795883-1ml

2, 4-difluoro-n-[2-methoxy-5-[4-(4-pyrazine)-6-quinoline]-3-pyridine]benzenesulfonylamine 10mM in DMSO 1ml Macklin 1086062-66-9, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：G795883-1ml

Product model：1ml

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2, 4-difluoro-n-[2-methoxy-5-[4-(4-pyrazine)-6-quinoline]-3-pyridine]benzenesulfonylamine 10mM in DMSO 1ml

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