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名称

H1-7（组蛋白H1磷酸化位点），PKA底物 TFA盐

英文别名

货号

H332884-1mg

包装规格

1mg

浓度

≥95%

产品介绍

H1-7（组蛋白H1磷酸化位点），PKA底物是一种合成的肽，可作为PKA（依赖cAMP的蛋白激酶）的假底物。该肽源于小牛胸腺组蛋白H1丝氨酸38的氨基酸序列，用于研究PKA催化亚基的反应机理。H1-7的磷酸化绝对催化速率比H1大，比整个组蛋白H1的绝对米氏常数大40倍，但亲和力较低。H1-7的肽序列：RRKASGP。 CAS：65189-70-0(free basis) 分子式：C31H58N14O9(free basis) 分子量：770.88(free basis) H1-7 (histone H1 phosphorylation site), PKA Substrate is a synthetic peptide that acts as a pseudo substrate for PKA (cAMP-dependent protein kinase). This peptide was derived from the calf thymus histone H1 amino acid sequence about serine-38 and was used to research the reaction mechanism of the PKA catalytic subunit. H1-7 exhibits a greater absolute catalytic rate of phosphorylation than H1, an absolute Michaelis constant 40-fold greater than whole histone H1, but exhibits less affinity. Peptide sequence of H1-7: RRKASGP.

序列

Arg-Arg-Lys-Ala-Ser-Gly-Pro

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