
- Hazard summary: 制药工人中报告有哮喘和过敏性接触性皮炎; [Malo] 在制药行业中为皮肤致敏物; 患者常与肼有交叉敏感性; [Kanerva, p. 1155]
- Harmful effect: 也有报道称有少数多发性神经炎病例可通过吡哆醇补充剂治疗。
- Toxicity summary: 关于肼屈嗪急性使用毒性的报道很少。毒性体征包括低血压、心动过速、头痛和全身潮红。慢性毒性可能导致DILE。除了支持性治疗外,没有特定的过量治疗方法。应首先给予液体,如果液体未能改善低血压,则应给予血管加压药。心动过速或缺血可使用β受体阻滞剂治疗,但给药前应注意血压。
- Hepatotoxicity: 可能性评分:A(已明确为引起明显肝损伤的原因)。
- Hazard categories and classifications: 特定靶器官毒性 - 重复暴露 - 1类 (免疫系统、血液)
- Carcinogen Classification: IARC专著:第7卷补充:致癌性总体评价:IARC专著第1至42卷的更新,1987年;440页;ISBN 92-832-1411-0 (已绝版)
- Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
- Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
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Research chemical 5mg; ≥98%
Research chemical 5mg; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥98%.
5mg




