Share to
Overview
Specs
Safety
Technical Documents
Related
Articles
reviews
Consult
returns
Product introduction
肼屈嗪是酞嗪的1-肼基衍生物;一种直接作用的血管扩张剂,用作抗高血压药。它具有血管扩张剂和抗高血压剂的作用。它是肼类、酞嗪类、氮杂芳烃和邻稠杂芳烃的成员。
Chinese name
肼屈嗪
English name
phthalazin-1-ylhydrazine
Chinese alias
双肼酞嗪杂质 | 1-肼基酞嗪
English alias
1-Phthalazinylhydrazine | Apresolin; Apresoline; Apressin | Hydralazine; phthalazin-1-ylhydrazine' | Hidral (TN) | NCGC00015501-03 | SPBio_000977 | CAS-304-20-1 | Hydralazine polistirex | Hydrazinophthalazine | Hidralazin | Hypophthalin | BDBM81461 | Hydr
CAS number
86-54-4
molecular formula
C8H8N4
molecular weight
160.18
Exact mass
-
PSA
63.8
Logp
0.7
Safety
  • Hazard summary: 制药工人中报告有哮喘和过敏性接触性皮炎; [Malo] 在制药行业中为皮肤致敏物; 患者常与肼有交叉敏感性; [Kanerva, p. 1155]
  • Harmful effect: 也有报道称有少数多发性神经炎病例可通过吡哆醇补充剂治疗。
  • Toxicity summary: 关于肼屈嗪急性使用毒性的报道很少。毒性体征包括低血压、心动过速、头痛和全身潮红。慢性毒性可能导致DILE。除了支持性治疗外,没有特定的过量治疗方法。应首先给予液体,如果液体未能改善低血压,则应给予血管加压药。心动过速或缺血可使用β受体阻滞剂治疗,但给药前应注意血压。
  • Hepatotoxicity: 可能性评分:A(已明确为引起明显肝损伤的原因)。
  • Hazard categories and classifications: 特定靶器官毒性 - 重复暴露 - 1类 (免疫系统、血液)
  • Carcinogen Classification: IARC专著:第7卷补充:致癌性总体评价:IARC专著第1至42卷的更新,1987年;440页;ISBN 92-832-1411-0 (已绝版)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2019.09.022
  • Effects During Pregnancy and Lactation: 截至修订日期,未找到相关已发表信息。
Technical Documents
「No technical documents」
Related
「No upstream and downstream information yet」
Articles
「No related articles yet」
user reviews
Loading...
Consultation

Warm reminder:

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.!

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ,We will handle it for you as soon as possible, thank you for your support and trust.!

Research chemical 5mg; ≥98%

Research chemical 5mg; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 5mg; ≥98%.

item number:H610884-5mg
Product model:5mg
level: 5mg; ≥98%
Lead Time:30days
sold 553 Items
Ask Solution engineer
Specifications:

5mg

Qty

Recommended for you