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Product details

名称

Honokiol DCA

别名

和厚朴酚DCA

英文名称

Honokiol DCA

货号

H655785-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level. In Vitro Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Honokiol类似物 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

Honokiol DCA（Honokiol 二氯乙酸盐）是 Honokiol 的二氯乙酸盐类似物。Honokiol DCA 可抑制体外人类前列腺癌细胞的生长，并抑制雄激素受体（AR）蛋白水平。

CAS号

1620160-42-0(DMSO)

分子式

C22H18Cl4O4

分子量

488.19 g/mol

Smiles

O=C(C(Cl)Cl)OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=C(OC(C(Cl)Cl)=O)C=C2

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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