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Product details

名称

HDAC-IN-4

英文名称

HDAC-IN-4

货号

H655876-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor with pIC 50 s of 7.2 and 6.8 in BRET assay, respectively. Antitumoral activity In Vitro HDAC-IN-4 inhibits HDAC1, HDAC2, HDAC3, HDAC8 and HDAC10 with pIC 50 s of 5.5, 4.6, 5.4, 5.4, 6.7 in FRET assay, respectively. HDAC-IN-4 is more potent against HDAC6 than Tubastatin A, suggests that HDAC-IN-4 may be a better HDAC6 probe than Tubastatin A. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:pIC50: 7.2 (HDAC6), and 6.8 (HDAC10)

生化机理

HDAC-IN-4 是一种选择性 HDAC6 和 HDAC10 抑制剂，在 BRET 试验中的 pIC 50 s 分别为 7.2 和 6.8。抗肿瘤活性。

CAS号

1252003-13-6(DMSO)

分子式

C20H22ClN3O2

分子量

371.87 g/mol

Smiles

CN1CCC2=C(C1)N(C3=CC=CC=C23)CC4=CC=C(C=C4)C(=O)NO.Cl

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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