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Product introduction

HBF-0259 is a potent and selective inhibitor of hepatitis B virus (HBV) surface antigen (HBsAg) secretion, with an EC 50 of 1.5 μM in HepG2.2.15 cells. HBF-0259 has no effect on HBV DNA synthesis. In Vitro HBF-0259 (0.0158-50.0 μM) inhibits the HBsAg secretion (EC 50 =1.5 μM) in HepDE19 cells, with an CC 50 of >50 μM. HBF-0259 (2-8 μM) significantly reduces the abundance of both L and M in the supernatants of HepG2.2.15 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

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Chinese name

HBF-0259

English name

HBF-0259

Chinese alias

English alias

CAS number

957011-15-3

molecular formula

C16H12Cl2FN5

molecular weight

364.20 g/mol

Exact mass

≥99%

PSA

Logp

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