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Product introduction

2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins.伯胺的硫醇化试剂。用于制备二硫化物或硫醚。应用：在 pH 7-10 下，通过脒键反应，得到游离巯基。可用于制备二硫化物和/或硫醚连接的缀合物。 2-硫代乙烯基盐酸盐已用于合成硫醇化 PEG（聚（乙二醇））。它可用于合成 PLA-SH（聚乙二醇-硫醇）和 PLA-PEG-SH（聚乙二醇-聚乳酸-硫醇）。 2-Iminothiolane, Hydrochloride is a thiolating agent that is useful in cross-linking proteins. A thiolane derivitization agent. Application： 2-Iminothiolane hydrochloride has been used in the synthesis of thiolated PEG (poly(ethylene glycol). It may be used to synthesize PLA-SH (polyethylene glycol-thiol) and PLA-PEG-SH (polyethylene glycol–polylactic acid-thiol). Thiolating reagent for primary amines. Reacts at pH 7-10 by amidine bond to present free sulfhydryl. Useful in preparation of disulfide and/or thioether linked conjugates.

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Chinese name

2-亚氨基硫杂环戊烷盐酸盐

English name

2-Iminothiolane hydrochloride

Chinese alias

English alias

CAS number

4781-83-3

molecular formula

C4H7NS·HCl

molecular weight

137.63 g/mol

Exact mass

≥98%

PSA

49.200 Å²

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