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Product introduction

丙咪嗪N-氧化物是叔胺氧化的形式，是三环血清素/多巴胺转运抑制剂咪咪嗪的天然代谢产物。利用结合的辅因子黄素进行氧化还原偶联，FMO（含黄素的单加氧酶）酶负责亲核杂原子（如亚丙美明的叔胺）的氧化。丙咪嗪N-氧化物可以用作调查FMO酶与FMO介导的丙咪嗪氧化有关的存在和活性的标准。丙咪嗪N-氧化物是FMO的底物。 Imipramine N-oxide is the tertiary amine-oxidized form and a natural metabolite of the tricyclic serotonin/dopamine transport inhibitor Imipramine . FMO (Flavin-containing monooxygenase) enzymes are responsible for the oxidation of nucleophilic heteroatoms such as the tertiary amine of Imipramine, utilizing the bound cofactor flavin for redox coupling. Imipramine N-oxide can be used as a standard for investigating the presence and activity of FMO enzymes in relation to the FMO-mediated oxidation of Imipramine. Imipramine N-oxide is a substrate of FMO.

Specs ⸢ View details ⸥

Chinese name

丙咪嗪N-氧化物

English name

Imipramine N-oxide

Chinese alias

English alias

CAS number

6829-98-7

molecular formula

C19H24N2O

molecular weight

296.4 g/mol

Exact mass

≥98%

PSA

21.300 Å²

Logp

4.800

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