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Product introduction

Information Imidazole ketone erastin (PUN30119) Imidazole ketone erastin (PUN30119, IKE) is a potent, selective, and metabolically stable system xc– inhibitor and inducer of ferroptosis . Targets Ferroptosis ; system xc– In vitro Imidazole ketone erastin (IKE) is an erastin analog with nanomolar potency, high metabolic stability, and intermediate water solubility. Its treatment potently reduces DLBCL cell number. Cell Research(from reference) Cell lines：DLBCL cell line Concentrations：0-100 μM Incubation Time：24 h

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Chinese name

咪唑酮伊拉斯汀(PUN30119)

English name

Imidazole ketone erastin (PUN30119)

Chinese alias

English alias

IKE | IKE4(3H)-Quinazolinone,2-[[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]methyl]-3-[5-[2-(1H-imidazol-1-yl)acetyl]-2-(1-methylethoxy)phenyl]-

CAS number

1801530-11-9

molecular formula

C35H35ClN6O5

molecular weight

655.14 g/mol

Exact mass

10mM in DMSO

PSA

110.000 Å²

Logp

4.057

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