3-IN-PP1 is a protein kinase D (PKD) inhibitor. 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1 , PKD2 and PKD3 with IC 50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 also is a broad spectrum anticancer agent and has inhibition of several tumor cells growth. 3-IN-PP1 can be used for the research of cancer In Vitro 3-IN-PP1 has potent pan-PKD inhibitory activity for PKD1, PKD2 and PKD3 with IC 50 values of 108, 94 and 108 nM, respectively. 3-IN-PP1 (5 μM, 0-114 h) displays potent anti-proliferative activity against PANC-1 cells. 3-IN-PP1 (20 μM, 1 h) potently blocks PKD-dependent cortactin phosphorylation in PANC-1 cells. 3-IN-PP1 has inhibition of different tumor cell growth with IC 50 values range from 1.6 to 39.2μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Proliferation AssayCell Line: PANC-1 cell Concentration: 5 μM Incubation Time: 0-114 h Result: Significantly inhibited PANC-1 cell proliferation after incubation for 96 and 144 hours. Western Blot AnalysisCell Line: PANC-1 cells Concentration: 20 μM Incubation Time: 1 h Result: Reduced cortactin phosphorylation in PANC-1 cells. Form:Solid IC50& Target:PKD1 108 nM (IC 50 ) Cellular PKD2 94 nM (IC 50 ) PKD3 108 nM (IC 50 )