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Product details

名称

INO-1001

分子类型

小分子

英文名称

INO-1001

货号

I656588-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

INO-1001 is a potent and selective poly (ADP-ribose) polymerase (PARP) inhibitor. INO-1001 is a potent enhancer of radiation sensitivity and enhances radiation-induced cell killing by interfering with DNA repair mechanisms, resulting in necrotic cell death INO-1001 has anti-tumor effects . In Vitro INO-1001 has an IC 50 of 0.05 μM in Chinese hamster ovary AA8 (CHO) cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:PARP

生化机理

INO-1001 是一种强效的选择性聚（ADP-核糖）聚合酶（PARP）抑制剂。INO-1001 能有效增强辐射敏感性，并通过干扰 DNA 修复机制增强辐射诱导的细胞杀伤力，导致坏死细胞死亡。

CAS号

501364-82-5(DMSO)

分子式

C23H25N3O4S

分子量

439.5 g/mol

Smiles

C1COCCN1CCCNS(=O)(=O)C2=CC3=C(C=C2)C4=C(C3)C5=CC=CC=C5C(=O)N4

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

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