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名称

iMDK quarterhydrate

别名

iMDK 四分之一水合物

英文名称

iMDK quarterhydrate

货号

I659360-5mg

包装规格

5mg

浓度

≥99%

储存温度

-20°C储存

运输条件

超低温冰袋运输

产品介绍

iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice Appearance:Solid In Vitro:iMDK (50-500 nM) quarterhydrate suppressed AKT phosphorylation in a dose-dependent manner in H441 lung adenocarcinoma cells after treatment for 72 h. In contrast, iMDK quarterhydrate robustly increases p-ERK. MCE has not independently confirmed the a In Vivo:The combination treatment of iMDK ( (9mg/kg/day; intraperitoneally injected with 100 μl) and PD0325901 (5mg/kg; orally administered) effectively reduced lung tumor growth in a xenograft mouse model. MCE has not independently confirmed the accuracy Biological Activity:iMDK quarterhydrate is a potent PI3K inhibitor and inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate suppresses non-small cell lung cancer (NSCLC) cooperatively with A MEK inhibitor without harming normal cells and mice

分子式

C21H13FN2O2S.1/4H20

分子量

380.91 g/mol

Smiles

O=C1C(C2=CN3C(SC(CC4=CC=C(F)C=C4)=C3)=N2)=CC5=CC=CC=C5O1.[1/4].O

溶解性

DMSO : 20 mg/mL (52.51 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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