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Product introduction

Irinotecan是一种Topoisomerase I抑制剂，作用于LoVo细胞和HT-29细胞，IC50分别为15.8 μM和5.17 μM。 Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. Irinotecan hydrochloride has been used: in combination with 5-fluorouracil for screening growth inhibitory functionality in MDA-MB-231 breast cancer cells. in chemosensitivity screening of high-grade appendiceal (HGA) and low-grade appendiceal (LGA) organoids. as a chemotherapeutic agent in the cytotoxicity studies in combination with heat shock proteins inhibitors (HPSC1) in HT29 colon cancer cells.

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Chinese name

伊立替康, DNA 拓扑异构酶 I 抑制剂

English name

Irinotecan

Chinese alias

伊立替康 | 依立替康 | (S)-4,11-二乙基-3,4,12,14-四氢-4-羟基-3,14-二氧代-1H-吡喃并[3′,4′:6,7]中氮茚并[1,2-b]喹啉-9-基酯 | [1,4′-联吡啶]-1′-羧酸

English alias

MFCD00866307 | AB00698464-10 | D08086 | (+)-7-ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate | (+)-Irinotecan | CPT-11

CAS number

97682-44-5

molecular formula

C33H38N4O6

molecular weight

586.68 g/mol

Exact mass

PSA

113.000 Å²

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Research chemical CAS 97682-44-5 10mM 1ml

Name: Research chemical CAS 97682-44-5 10mM 1ml
Brand: 麦克林
SKU: I793967-1ml

Research chemical CAS 97682-44-5 10mM 1ml, complete specifications, for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number：I793967-1ml

Product model：1ml

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Lead Time：30days

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Research chemical CAS 97682-44-5 10mM 1ml

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