
- exposure pathway: 口服、皮肤接触、吸入和注射(受污染药物)。(A3101)
- Toxicity summary: 部分鹅膏氨酸代谢为鹅膏蕈氨酸,一种强效GABAA激动剂,激活大脑主要抑制性神经递质GABA的受体。鹅膏蕈氨酸实际上与GABA本身结合到GABAA受体复合物的相同结合位点,而其他GABA能药物如巴比妥类和苯二氮䓬类则结合到不同的调节位点。GABAA受体广泛分布于大脑中,因此当给予鹅膏蕈氨酸时,它会改变多个区域的神经元活动,包括大脑皮层、海马和小脑。然而,虽然鹅膏蕈氨酸通常被认为是选择性GABAA激动剂,但它也是GABAC受体的强效部分激动剂,因此其效果特征是两个靶点共同作用的结果。(L1142, L...
- Health Effects: 鹅膏氨酸具有神经毒性。(L1141)
- Symptoms and Signs: 当鹅膏氨酸被摄入时,一小部分会脱羧成鹅膏蕈氨酸。人类在50-100mg剂量范围内会引发致幻效果。口服摄入后约2-3小时达到中毒高峰,包括以下一种或全部:视觉扭曲/幻觉、平衡感丧失、肌肉抽搐(常被误标为惊厥)和感觉感知改变。这些效果通常持续6-8小时,因剂量而异。(L1141)
- Hazard categories and classifications: 急性毒性 3 (100%)
- Carcinogen Classification: 对人类无致癌性迹象(未被IARC列出)。
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Ibotenic acid ≥98% 5mg
Ibotenic acid ≥98% 5mg CAS 2552-55-8, complete specifications for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.




