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Product introduction

JKE-1716 is a potent and selective nitrolic acid-containing GPX4 inhibitor. JKE-1716 is able of inducing ferroptosis selectively through covalent GPX4 inhibition In Vitro JKE-1716 (0~100 nΜ; 72 hours; LOX-IMVI cells) inhibits cell viability. JKE-1716 (LOX-IMVI cells) inhibits the expression of α-GPX4. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: LOX-IMVI cells Concentration: 0~100 nΜ Incubation Time: 72 hours Result: Inhibited cell viability. Form:Solid IC50& Target:GPX4, ,Ferroptosis

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Chinese name

JKE-1716

English name

JKE-1716

Chinese alias

English alias

CAS number

2421118-05-8

molecular formula

C20H20Cl2N4O4

molecular weight

451.30 g/mol

Exact mass

≥98%

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