Share to

Overview

Specs

Technical Documents

Articles

reviews

Consult

returns

Product introduction

JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs ( JHDM ) inhibitor with IC 50 s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively In Vitro JHDM-IN-1 (Compound 1) also inhibits FIH, PHD3, PHD1, PHD2 and LSD1 with IC 50 s of 22, 31, 54, 83 and 620 μM, respectively. JHDM-IN-1 (0-100 μM) does not inhibit KYSE150 cell growth after treatment for 48 h. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 3.4 μM (JMJD2C), 4.3 μM (JMJD2A), 5.9 μM (JMJD2E), 10 μM (PHF8), 22 μM (FIH), 31 μM (PHD3), 43 μM (JMJD3), 54 μM (PHD1), 83 μM (PHD2), 620 μM (LSD1)

Specs ⸢ View details ⸥

Chinese name

JHDM-IN-1

English name

JHDM-IN-1

Chinese alias

English alias

CAS number

1310809-17-6

molecular formula

C27H29N3O6

molecular weight

491.54 g/mol

Exact mass

PSA

Logp

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！