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Product introduction

JQ1 是三唑并二氮嗪化合物家族的一员，作为pan-BET（溴结构域和额外终端域）家族抑制剂发挥作用。已知 JQ1 可抑制细胞增殖，因此，可用作许多癌症的治疗药物，包括多发性骨髓瘤和急性髓性白血病。 JQ1 is a member of the triazolo-diazepine compound family, which functions as a pan-BET (bromodomain and extra-terminal motif) family inhibitor. JQ1 is known to suppress cell proliferation and therefore, can be used as a therapeutic drug for a number of cancers including multiple myeloma and acute myeloid leukemia. Product Application： (+)-JQ1 has been used in flow cytometry assay, cell viability assay and quantitative PCR assay in order to investigate on the reversal of HIV-1 latency.

Specs ⸢ View details ⸥

Chinese name

(+)-JQ1,BET溴结构域抑制剂

English name

(+)-JQ1

Chinese alias

(S)-(+)-叔丁基 2-(4-(4-氯苯基)-2,3,9-三甲基-6H-噻吩 [3,2-f][1,2,4] 三唑并[4,3-a][1,4] 二氮杂卓-6-基)乙酸酯 | 6H-噻吩并[3,2-f] [1,2,4] 三唑并[4,3-a][1,4] 二氮杂卓-6-乙酸 | 4-(4-氯苯基)-2,3,9-三甲基-,1,1-二甲基乙酯

English alias

Tox21_303984 | (6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester | Q3156953 | A854208 | NSC760183 | NSC-760183 | tert-butyl 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thie

CAS number

1268524-70-4

molecular formula

C23H25ClN4O2S

molecular weight

456.99 g/mol

Exact mass

≥98%(HPLC)

PSA

97.600 Å²

Logp

4.900

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(+)-JQ-1 10mM in DMSO 1ml

Name: (+)-JQ-1 10mM in DMSO 1ml
Brand: 麦克林
SKU: J798301-1ml

(+)-JQ-1 10mM in DMSO 1ml Macklin 1268524-70-4, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：J798301-1ml

Product model：1ml

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Lead Time：30days

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(+)-JQ-1 10mM in DMSO 1ml

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