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Product introduction

KX2-361 (KX-02) 是一种 Src 激酶和微管蛋白 (tubulin) 聚合抑制剂。 KX2-361 在小鼠体内表现出良好的口服生物利用度并易于穿过血脑屏障。 KX2-361 具有抗肿瘤活性，并能诱导胶质母细胞瘤 (GBM) 细胞凋亡 (apoptosis)。 KX2-361 (KX-02) is a Src-kinase and tubulin polymerization inhibitor. KX2-361 shows good oral bioavailability and readily crosses the BBB in mice. KX2-361 shows anti-tumor activity and induces apoptosis of Glioblastoma (GBM) cell.

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Chinese name

KX2-361, SRC 原癌基因抑制剂

English name

KX2-361

Chinese alias

English alias

CAS number

897016-26-1

molecular formula

C24H24FN3O2

molecular weight

405.46 g/mol

Exact mass

PSA

54.500 Å²

Logp

3.100

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