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名称

KDM5-C49 hydrochloride

别名

KDM5-C49盐酸盐

英文名称

KDM5-C49 hydrochloride

货号

K658789-5mg

包装规格

5mg

浓度

≥99%

储存温度

2-8°C储存,干燥

运输条件

冰袋运输

产品介绍

KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer Appearance:Solid-liquid mixture In Vitro:KDM5-C49 hydrochloride display poor permeability. Convert the carboxylate group of KDM5-C49 into an ethyl ester, to get a cell-permeable prodrug (KDM5-C70). MCE has not independently confirmed the accuracy of these methods. They are for reference onl Biological Activity:KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer

分子式

C15H25ClN4O3

分子量

344.84 g/mol

Smiles

O=C(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)O.[H]Cl

溶解性

DMSO : 125 mg/mL (362.49 mM; Need ultrasonic)

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

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「No related articles yet」

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