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Product introduction
KRAS inhibitor-9 是一种 KRAS 抑制剂,阻止 GTP-KRAS 的形成和 KRAS 下游激活。它以中等的结合亲和力与 KRAS G12D、KRAS G12C 和 KRAS Q61H 蛋白结合,选择性抑制具有 KRAS 突变的 NSCLC 细胞的增殖。它可导致 G2/M 细胞周期停滞并诱导凋亡。 Information 0375-0604 (KRAS inhibitor-9, DUN09716) is a potent KRAS inhibitor with Kd of 92 μM that blocks the formation of GTP-KRAS and downstream activation of KRAS. 0375-0604 (KRAS inhibitor-9, DUN09716) causes G2/M cell cycle arrest and induces apoptosis.
Chinese name
0375-0604(KRAS抑制剂-9)
English name
0375-0604 (KRAS inhibitor-9)
Chinese alias
-
English alias
DUN09716
CAS number
300809-71-6
molecular formula
C13H9ClN2S2
molecular weight
292.81 g/mol
Exact mass
≥98%
PSA
92.500 Ų
Logp
4.700
Technical Documents
「No technical documents」
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4-(benzo[d]thiazol-2-ylthio)-3-chloroaniline 10mM in DMSO 1ml

Macklin 4-(benzo[d]thiazol-2-ylthio)-3-chloroaniline 10mM in DMSO 1ml, CAS 300809-71-6, complete specifications; suitable for production, research, laboratory testing and inspection; digital one-stop procurement platform for scientific materials.

item number:K688771-1ml
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