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Product introduction

Ki20227 是一种高选择性 CSF1R (c-Fms 酪氨酸激酶)抑制剂，对 CSF1R，VEGFR2 (血管内皮生长因子受体 2)，c-Kit (干细胞因子受体) 和 PDGFRβ (血小板衍生的生长因子受体 β) 的 IC50 分别为 2 nM，12 nM，451 nM 和 217 nM。Ki20227 可以抑制破骨细胞分化和溶骨性破坏。 Product description： Ki20227 is a highly selective c-Fms tyrosine kinase (CSF1R) inhibitor with IC50s of 2 nM, 12 nM, 451 and 217 nM for CSF1R, VEGFR2 (vascular endothelial growth factor receptor-2), c-Kit (stem cell factor receptor) and PDGFRβ (platelet-derived growth factor receptor β). Ki20227 suppresses osteoclast differentiation and osteolytic bone destruction.

Specs ⸢ View details ⸥

Chinese name

Ki20227,c-Fms抑制剂, 集落刺激因子 1 受体抑制剂

English name

Ki20227

Chinese alias

English alias

CAS number

623142-96-1

molecular formula

C24H24N4O5S

molecular weight

480.55 g/mol

Exact mass

PSA

132.000 Å²

Logp

3.600

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Ki20227 10mM in DMSO 1ml

Name: Ki20227 10mM in DMSO 1ml
Brand: 麦克林
SKU: K795191-1ml

Ki20227 10mM in DMSO 1ml Macklin 623142-96-1, complete specifications, for production, research, laboratory testing and inspection, digital one-stop procurement platform for scientific materials.

item number：K795191-1ml

Product model：1ml

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Lead Time：30days

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Ki20227 10mM in DMSO 1ml

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