肌酸磷酸激酶

L1491909-10KU

10KU

天然

≥300 U/mg protein

肌酸磷酸激酶（CPK）分布广泛，主要与收缩系统和转运系统协同参与 ATP 的再生。该酶为二聚体，存在三种同工酶形式：MM 型（肌肉型）、MB 型（心脏型）和 BB 型（脑型）。杂交同工酶（MB 型）在心肌中浓度最高，因此，测定血清中该同工酶的肌酸磷酸激酶水平已被用作诊断心肌梗死的敏感指标。 据报道，心脏手术后患者的血清中，肌酸磷酸激酶 BB 型同工酶水平会立即升高，而到术后第四天，血清中肌酸磷酸激酶 BB 型水平可恢复正常。对于心脏病患者而言，这可能是一种比血清肌酸磷酸激酶 MB 型同工酶水平更敏感的诊断工具。 Creatine phosphokinase (CPK) is widely distributed and is primarily involved with ATP regeneration in conjunction with the contractile and transport systems. The enzyme is dimeric and exists in three isoenzyme forms: MM (muscle), MB (heart) and BB (brain). The hybrid isoenzyme (MB) has the highest concentration in the heart muscle. Therefore, determination of the serum CPK level of this isoenzyme has been used as a sensitive index for the diagnosis of myocardial infarction. Elevated levels of the BB isoenzyme of CPK have been reported in the serum of patients immediately following cardiac surgery. The CPK-BB levels in serum returned to normal by the fourth post-operative day. This may be a more sensitive diagnostic tool than the serum levels of CPK-MB isoenzyme in cardiac patients.

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

≥300 U/mg protein

天然

Pig