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Product introduction

PF-07304814 是 PF-00835231 的磷酸盐前药，可结合并抑制 SARS-CoV-2 3CLpro 活性，Ki 为 174 nM。

Specs ⸢ View details ⸥

Chinese name

Lufotrelvir (PF-07304814)

English name

Lufotrelvir (PF-07304814)

Chinese alias

卢福瑞韦 (PF-07304814)

English alias

Lufotrelvir [WHO-DD] | EX-A4702 | LUFOTRELVIR [INN] | 4-Methoxy-N-((2S)-4-methyl-1-oxo-1-(((2S)-3-oxo-1-((3S)-2-oxopyrrolidin-3-yl)-4-(phosphonooxy)butan-2-yl)amino)pentan-2-yl)-1H-indole-2-carboxamide | Lufotrelvir | (3S)-3-{[(2S)-2-{[(4-methoxy-1H-indol

CAS number

2468015-78-1

molecular formula

C24H33N4O9P

molecular weight

552.51 g/mol

Exact mass

PSA

196.000 Å²

Logp

0.500

Technical Documents

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