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生化/生理作用丝氨酸和半胱氨酸蛋白酶抑制剂。抑制纤溶酶、胰蛋白酶、木瓜蛋白酶、钙蛋白酶和组织蛋白酶B。不抑制胃蛋白酶、组织蛋白酶A和D、凝血酶或α-糜蛋白酶。有效浓度为10-100 μM.已有许多研究使用亮抑酶肽来预防因听觉过度刺激或耳毒性抗生素庆大霉素引起的听力损失。(耳蜗毛细胞的丧失被认为是由钙蛋白酶介导的。) 产品描述由于三种形式在溶液中达到平衡，亮抑酶肽可在 HPLC 上形成多个峰。通过三个主峰测定纯度。主要的杂质肽为外消旋亮抑酶肽。 A reversible inhibitor of cysteine proteases and serine proteases resembling trypsin Reversible inhibitor Ultra pure grade Inhibits trypsin, plasmin, papain, kallikrein, thrombin and cathepsin A and B.

Specs ⸢ View details ⸥

Chinese name

亮肽素

English name

Leupeptin

Chinese alias

N-乙酰基-L-亮氨酰-L-亮氨酰-L-精氨醛半硫酸盐 | 亮抑酶肽半硫酸盐

English alias

CAS number

103476-89-7

molecular formula

C20H38N6O4·1/2(H2SO4)

molecular weight

475.59 g/mol

Exact mass

PSA

421.000 Å²

Logp

Technical Documents

103476-89-7 | Leupeptin hemisulfate salt.pdf
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