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Product introduction

Ruboxistaurin (LY333531) hydrochloride 是一种具有口服活性，选择性 PKC beta 抑制剂(Ki=2 nM)，Ruboxistaurin hydrochloride 表现出 ATP 依赖的竞争性抑制 PKC beta I，其 IC50 为4.7 nM。Ruboxistaurin hydrochloride 对 PKC beta II 的 IC50 为 5.9 nM。应用： LY-333531盐酸盐/ruboxistaurin已被用作PKCB阻断剂，以比较来源于受刺激的野生型细胞的磷酸肽与来源于PKCB敲除细胞或野生型细胞的磷酸肽。 Shipped at 4°C. Store at -20°C. Store under desiccating conditions.

Specs ⸢ View details ⸥

Chinese name

LY-333531盐酸盐

English name

LY-333531 hydrochloride

Chinese alias

(9S)-9-[((二甲氨基)甲基]-6,7,10,11-四氢-9H,18H-5,21：12,17-二甲基二苯并[e,k]吡咯并[3,4-h][1,4,13]草二氮杂环己癸-18,20(19H)-二酮盐酸盐

English alias

LY333531 HCl | (9S)-9-[(DiMethylaMino)Methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-DiMethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione Hydrochloride;LY333531 Hydrochloride | 9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[

CAS number

169939-93-9

molecular formula

C28H28N4O3 · HCl

molecular weight

505.01 g/mol

Exact mass

10mM in DMSO

PSA

68.500 Å²

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