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Product introduction

储存在-20℃（干燥条件下）。描述 L-685,458 是一种beta PP gamma-secretase活性的特异性有效抑制剂，其Ki值为17 nM.。应用 L-685,458已被用于减弱卵巢培养中的Notch信号转导。它已被用于分析脑组织样本中γ-分泌酶活性的特异性。 Store at -20°C (desiccating conditions). application L-685,458 has been used to attenuate Notch signalling in ovary culture. It has also been used to analyze the specificity of the γ-secretase activity in brain tissue samples.

Specs ⸢ View details ⸥

Chinese name

L-685,458

English name

L-685,458

Chinese alias

(5S)-(叔丁氧羰基氨基)-6-苯基-(4R)-羟基-(2R)-苄基己酰基)-L-亮氨酰-L-苯基丙氨酰胺

English alias

NCGC00165962-01 | HY-19369 | L 458 | (5S)-[tert-butoxycarbonylamino-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl]-L-Leu-L-Phe-NH2 | CHEBI:74921 | L-68458 | BCP22749 | tert-butyl ((2S,3R,5R)-6-(((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-4-methyl-1-

CAS number

292632-98-5

molecular formula

C39H52N4O6

molecular weight

672.85 g/mol

Exact mass

10mM in DMSO

PSA

160.000 Å²

Logp

5.900

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