Share to

Details

Safety

Technical Documents

Articles

reviews

Consult

returns

Product details

名称

L-372662

英文名称

L-372662

货号

L654535-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

L-372662 is a potent and orally active non-peptide oxytocin antagonist with a K i value of 4.8. The K d value of L-372662 for wild-type hOTR and [A318G]OTR is 5.8 nM and 73 nM. L-372662 shows selectivity to OTR:V 1a R In Vivo L-372662 is an antagonist of oxytocin-induced uterine contractions in late gestation pregnant rhesus monkeys (AD50 = 36 micrograms/kg), oral bioavailability (F = 90% in dogs), and aqueous solubility (10 mg/mL). MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:Ki: 4.8 (oxytocin)

生化机理

L-372662 是一种强效的口服活性非肽催产素拮抗剂，其 K i 值为 4.8。L-372662 对野生型 hOTR 和 [A318G]OTR 的 K d 值分别为 5.8 nM 和 73 nM。L-372662 对 OTR:V 1a R 具有选择性。

CAS号

162045-26-3(DMSO)

分子式

C33H38N4O6

分子量

586.68 g/mol

Smiles

CC1=C(C=CC=[N+]1[O-])CN2CCC(CC2)OC3=CC(=C(C=C3)C(=O)N4CCC(CC4)N5C6=CC=CC=C6COC5=O)OC

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

user reviews

Consultation

Warm reminder：

Because the manufacturer may temporarily adjust product specifications, prices, inventory, parameters and other information without notice, and there are differences in each user's consultation time and procurement needs, the platform reply content is only of reference value within a certain period. Sorry for the inconvenience caused to you, and thank you for your understanding and support! Please consult the online customer service for the latest details. Everything is subject to the real-time reply of the customer service.！

After Sales Services

Please check the quantity, appearance and product information in time when you receive the goods. In case of damage, wrong delivery, abnormal quality and other problems, please feel free to contact us.

Service Hotline:400-6226-992 ，We will handle it for you as soon as possible, thank you for your support and trust.！