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Product details

名称

LCL521

英文名称

LCL521

货号

L654945-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

LCL521 is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase ) In Vitro LCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:ACDase, ASMase

生化机理

LCL521 是一种酸性神经酰胺酶（ACDase）抑制剂。LCL521 还能抑制溶酶体酸性鞘磷脂酶（ASMase）。

CAS号

1226851-11-1(DMSO)

分子式

C31H52N4O7

分子量

592.77 g/mol

Smiles

CCCCCCCCCCCCCC(=O)NC(COC(=O)CN(C)C)C(C1=CC=C(C=C1)[N+](=O)[O-])OC(=O)CN(C)C

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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