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Product details

名称

Lipofermata

别名

脂强化菌

英文名称

Lipofermata

货号

L655036-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

Lipofermata is a fatty acid transport protein 2 (FATP2) inhibitor. Lipofermata shows fatty acid transport inhibition with an IC 50 of 4.84 μM in Caco-2 cells. Lipofermata, an analog of spiro-indoline-thadiazole, shows zinc-specific suppression of antibacterial activity. Lipofermata perturbs zinc homeostasis in E. coli K-12 with a MIC of 16 μM . In Vitro Lipofermata inhibits C1-BODIPY-C12 transport into C2C12, INS-1E, Caco-2 and HepG2 cells at comparable levels yielding sigmoidal dose-response curves with IC 50 s in the low micromolar range (IC 50 =2.74-39.34 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only.

生化机理

Lipofermata 是一种脂肪酸转运蛋白 2（FATP2）抑制剂。Lipofermata 可抑制脂肪酸转运，在 Caco-2 细胞中的 IC 50 为 4.84 μM。Lipofermata 是螺吲哚啉-噻二唑的类似物，具有锌特异性抗菌抑制作用。

CAS号

297180-15-5(DMSO)

分子式

C15H10BrN3OS

分子量

360.2 g/mol

Smiles

C1=CC=C(C=C1)C2=NNC3(S2)C4=C(C=CC(=C4)Br)NC3=O

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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