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Product details

名称

LY3154207

分子类型

小分子

英文名称

LY3154207

货号

L656763-1ml

包装规格

1ml

浓度

10mM in DMSO

储存温度

-80℃储存

运输条件

超低温冰袋运输

产品介绍

LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM) In Vitro In HEK293 cells transiently expressing human, dog, rhesus monkey, and mouse D1 receptors, the EC 50 s of LY3154207 are 2.3 nM, 2.0 nM, 2.5 nM, and 62.1 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:EC50: 3 nM (human dopamine D1 receptor)

生化机理

LY3154207 是一种强效的亚型选择性口服人多巴胺 D1 受体正性异位调节剂（PAM），具有最小异位激动剂活性（EC 50 =3 nM）。

CAS号

1638667-79-4(DMSO)

分子式

C24H29Cl2NO3

分子量

450.40 g/mol

Smiles

CC1C2=CC=CC(=C2CC(N1C(=O)CC3=C(C=CC=C3Cl)Cl)CO)CCC(C)(C)O

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

「No technical documents」

Articles

「No related articles yet」

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