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名称

LXW7 TFA

别名

LXW7 三氟乙酸

英文名称

LXW7 TFA

货号

L658923-5mg

包装规格

5mg

浓度

≥98%

储存温度

干燥,-80℃储存

运输条件

超低温冰袋运输

产品介绍

LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC 50 of 0.68 μM. LXW7 TFA increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory e Appearance:Solid IC50& Target:IC50: 0.68 μM (αvβ3 integrin) In Vitro:LXW7 specially binds to αvβ3 integrin (K d =76±10 nM). LXW7 binds strongly to αvβ3-K562 cells, weakly to αvβ5-K562 cells and αIIbβ3-K562 cells, and no binding to K562 cells. LXW7 has great potential as a highly efficient peptide ligand for targeted imagin In Vivo:LXW7 (100 μg/kg; intravenous injection) significantly lowers infarct volumes and brain water content (BWC) LXW7-treated rats. The LXW7 treatment lowers the expression of pro-inflammatory cytokines. MCE has not independently confirmed the accuracy of Biological Activity:LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor. LXW7 has a high binding affinity to αvβ3 integrin with an IC 50 of 0.68 μM. LXW7 TFA increases phosphorylation of VEGFR-2 and activation of ERK1/2. Anti-inflammatory e

分子式

C31H49F3N12O14S2

分子量

934.92 g/mol

溶解性

H2O Peptide Solubility and Storage Guidelines: 1.Calculate the length of the peptide. 2.Calculate the overall charge of the entire peptide according to the following table: Contents Assign value Acidic amino acid Asp (D), Glu (E), a

Safety

「No Dangerous Attributes」

「No upstream and downstream information yet」

Technical Documents

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