来自西非单叶豆（加纳籽）的凝集素

Lectin from Bandeiraea simplicifolia (Griffonia simplicifolia)

L755145-0.2mg

0.2mg

Isolectin B4 (BSI-B4), FITC conjugate, lyophilized powder

2-8°C储存

冰袋运输

来自西非单叶豆（加纳籽）的凝集素已用于鼠星形胶质细胞培养物中的小胶质细胞检测，检测方法是采用凝集BS1-B4对培养物进行染色。它还用于制备孵育组织切片的染色溶液。应用： 凝集素是碳水化合物结合蛋白，广泛存在于真菌、植物和动物中。凝集素结构在动植物领域经过广泛研究。该蛋白质的二级结构富含β-链，并且在表面上具有碳水化合物结合位点。 Lectins are carbohydrate-binding proteins, omnipresent, found in fungi, plants and animals. The structure of lectin is diversely studied in plants and animals. The secondary structure of this protein is rich in β-strands and possesses carbohydrate binding sites on the surface. Application: Lectin from Bandeiraea simplicifolia ( Griffonia simplicifolia ) has been used for microglia detection in murine astrocytes culture by staining the culture with lectin BS1-B4. It has also been used in the preparation of staining solution to incubate the tissue sections.

目前确知凝集素可用于鉴定、成像和靶向糖缀合物。由于与寡糖、糖蛋白和糖脂存在特异性相互作用，其还可用于芯片分析，实现有效的糖组图谱分析。在植物和真菌体内，凝集素可防御病原体/寄生物。凝集素参与宿主识别和组织粘附，有助于探索微生物的病理。BS-I对末端α-D-半乳糖残基具有主要亲和力，对末端N-乙酰基-α-D-半乳糖胺残基具有二级亲和力。