GPCR化合物库

GPCR Compound Library

Lib412031-100μl-well

100μl/well

-80℃储存

超低温冰袋运输

描述及优势 • 提供1136种靶向G蛋白偶联受体的小分子，可用于高通量筛选和高内涵筛选 • GPCR化合物库中的所有小分子都具有良好的生物和药学活性 • 一项发现GPCR药物是最丰富信号受体的有力工具 • 据估计大约200个“孤儿”GPCR功能是未知的，因此，使用我们的GPCR小分子化合物库来筛选功能未知的GPCR可能会产生潜在的新型GPCR候选药 • GPCR化合物库含有与受体相关的小分子， 包括5-HT 受体、多巴胺受体、阿片受体、肾上腺素受体、大麻素受体、mGluR和 ETA-受体等 • 结构多样，药效显著，可渗透细胞 • 具有充分详细的结构说明及客户反馈资料 • NMR和HPLC技术保证产品高纯度 详细信息 配制 1035个化合物预溶于10mM DMSO，67个化合物预溶于10mM水,30个化合物预溶于2mM DMSO，4个化合物预溶于2mM水 容器 带有螺旋盖和二维码的96孔储存管 储存条件 1年 -20°C溶于DMSO 2年 -80°C溶于DMSO •A unique collection of 1136 small molecules targeting G protein coupled receptors for high throughput screening (HTS) and high content screening (HCS) • All of the small molecules in the GPCR library are well characterized with biological and pharmaceutical activity • A powerful tool for discovering GPCR-based drugs that are the richest signal receptor targets for drug discovery • It is estimated about 200 so-called orphan GPCRs are functionally unknown, as a result, use of our GPCR Small Molecule Compound Library for screening the functionally unknown GPCRs may yield potentially new GPCR-based drug candidates • The GPCR compound library contains small molecules associated with receptors including 5-HT Receptor, Dopamine Receptor, Opioid Receptor, Adrenergic Receptors, Cannabinoid Receptor, mGluR, and ETA-receptor etc. • Structurally diverse, medicinally active, and cell permeable • Rich documentation with structure and customer reviews • NMR and HPLC validated to ensure the highest purity Product Details Formulation 1035 compounds pre-dissolved in 10mM DMSO，67 compounds pre-dissolved in 10mM H2O,30 compounds pre-dissolved in 2mM DMSO，4 compounds pre-dissolved in 2mM H2O Container 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode Stability 12 months -20°C in DMSO 24 months -80°C in DMSO GPCR Compound Library Composition