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Product introduction
根据世界卫生组织国际癌症研究机构(IARC),醋酸甲羟孕酮可致癌。根据州或联邦政府标签要求,它可导致发育毒性。
Chinese name
醋酸甲羟孕酮, 孕酮受体激动剂
English name
[(6S,8R,9S,10R,13S,14S,17R)-17-acetyl-6,10,13-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate
Chinese alias
安宫黄体酮 | 甲孕酮 | 17-乙酸甲羟孕酮 | 17α-乙酰氧基-6α-甲基黄体酮 | 17-乙酸17α-乙酰氧基-6α-甲基-4-孕烯-3,20-二酮
English alias
Clinovir | DP150 | Medroxyprogesterone acetate (Standard) | Pregn-4-ene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6alpha)- | Depocon | Veramix | Depo-subq provera | MAP | Veraplex | 6-alpha-Methyl-17-alpha-acetoxyprogesterone | 6alpha-Methyl-17alpha-acetoxyp
CAS number
71-58-9
molecular formula
C24H34O4
molecular weight
386.5
Exact mass
-
PSA
60.4
Logp
4.1
Safety
  • Health hazard: 急性/慢性危害:该化合物在分解时会产生刺激性烟雾和刺激性气体。(NTP,1992)
  • reactive group: 脂肪族不饱和烃
  • First aid measures: 其他:由于该化学物质是已知或可疑致癌物,您应咨询医生有关可能的长期健康效应和潜在的医疗监测建议。医生的建议将取决于特定化合物及其化学、物理和毒性特性、暴露水平、暴露时间和暴露途径。(NTP, 1992)
  • exposure pathway: 从胃肠道迅速吸收
  • Toxicity summary: 孕激素自由扩散到女性生殖道、乳腺、下丘脑和垂体的靶细胞中,并与孕酮受体结合。一旦与受体结合,孕激素会减缓下丘脑促性腺激素释放激素(GnRH)的释放频率,并减弱排卵前的LH峰。
  • Regulatory information: 新西兰EPA化学品清单状态:醋酸甲羟孕酮:没有单独批准,但可在适当的团体标准下使用
  • fire hazard: 该化学品的闪点数据不可用;但可能是可燃的。(NTP, 1992)
  • fire fighting: 涉及此材料的火灾可以用干化学灭火器、二氧化碳或哈龙灭火器控制。(NTP, 1992)
  • reactivity profile: 醇与碱金属、氮化物和强还原剂结合会产生易燃和/或有毒气体。它们与含氧酸和羧酸反应生成酯和水。氧化剂将它们转化为醛或酮。醇表现出弱酸和弱碱行为。它们可能引发异氰酸酯和环氧乙烷的聚合。
  • reactive alarm: 已知催化活性
  • Symptoms and Signs: 副作用包括骨矿物质密度降低、成年女性骨密度变化、出血不规则、癌症风险和血栓栓塞性疾病。
  • Other safety information: 化学品评估:IMAP评估 - 孕-4-烯-3,20-二酮,17-(乙酰氧基)-6-甲基-,(6α)-: 人类健康I级评估
  • Air and water reaction: 该化学品对长期暴露于空气和光敏感。不溶于水。
  • Hazard categories and classifications: 水生慢性4级(17.5%)
  • Non-fire leakage response: 储存注意事项:应保护此化学品免受光照。将容器紧密封闭在惰性气氛下,并在冷藏温度下储存。(NTP, 1992)
  • Personal protective equipment (PPE): 推荐呼吸器:在称量和稀释纯测试化学品时,佩戴NIOSH批准的半面罩呼吸器,配备组合滤毒罐,即有机蒸气/酸性气体/HEPA(专门针对有机蒸气、HCl、酸性气体、SO2和高效颗粒物过滤器)。(NTP, 1992)
  • Carcinogen Classification: 2B,可能对人类致癌。(L135)
  • Drug Induced Liver Injury: 参考文献:DOI:10.1016/j.drudis.2016.02.015
  • Effects During Pregnancy and Lactation: 尚未进行关于醋酸甲羟孕酮是否可能影响男性生育能力(使伴侣怀孕)或增加高于背景风险的出生缺陷几率的调查研究。通常,父亲或精子捐献者的暴露不太可能增加妊娠风险。更多信息,请参阅MotherToBaby信息表父系暴露,网址为https://mothertobaby.org/fact-sheets/paternal-exposures-pregnancy/。
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Research chemical 100g; ≥98%

Research chemical 100g; ≥98%; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100g; ≥98%.

item number:M129409-100g
Product model:100g
level: 100g; ≥98%
Lead Time:30days
sold 275 Items
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100g

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