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物理描述 | 乙基仲戊基酮为无色透明液体,有刺激性气味。不溶于水,部分溶于酒精。蒸气密度比空气大,高浓度下可能有麻醉作用。用于制造香水,并作为硝化纤维和乙烯基树脂的溶剂。
Chinese name
5-甲基-3-庚酮
English name
5-methylheptan-3-one
Chinese alias
-
English alias
(?à)-5-Methyl-3-heptanone; 2-Methylbutyl ethyl ketone; 3-Methyl-5-heptanone; 5-Methyl-3-heptanone; Ethyl2-methylbutyl ketone; NSC 100734
CAS number
541-85-5
molecular formula
C8H16O
molecular weight
128.21
Exact mass
-
PSA
17.1
Logp
2.2
Safety
  • EC classification: 符号: Xi; R: 10-36/37; S: (2)-23
  • UN classification: UN危险类别:3;UN包装组:III
  • DOT label: 易燃液体
  • Health hazard: ERG2024, 指南 128 (乙基戊基甲酮): · 灭火或稀释水产生的径流可能造成环境污染。
  • Hazard summary: 动物吸入研究中引起麻醉。以 820 mg/kg/天剂量喂养的动物出现外周神经病变的证据。[ACGIH] 皮肤、眼睛和呼吸道刺激物;吸入高浓度可引起中枢神经系统抑制;[ICSC]
  • reactive group: 酮类
  • inhalation prophylaxis: 使用通风、局部排气或呼吸防护。
  • Aspiration risk: 在20°C下蒸发此物质时,空气中有害污染物的形成将相当缓慢。
  • Safe storage: 防火。与强氧化剂、强碱和强还原剂分开存放。密闭保存。
  • First aid measures: 食入急救:漱口。喝一两杯水。就医。
  • ingestion prevention: 工作期间不要进食、饮水或吸烟。
  • flammable limit: 易燃性:II类可燃液体:闪点在100°F及以上且低于140°F。
  • exposure pathway: 吸入,食入,皮肤和/或眼睛接触
  • Harmful effect: 神经毒素 - 急性溶剂综合征
  • Spill disposal: 个人防护:适用于该物质空气浓度的有机气体和蒸气滤罐式呼吸器。通风。移除所有点火源。尽可能将泄漏和溢出的液体收集在密封容器中。用沙子或惰性吸收剂吸收剩余液体。然后根据当地法规储存和处置。切勿将其冲入下水道。
  • fire hazard: 易燃。高于 43 °C 时可能形成爆炸性蒸气/空气混合物。
  • fire fighting: Use water spray, powder, foam, carbon dioxide. In case of fire: keep cylinder cool by spraying with water.
  • fire prevention: 禁止明火、火花和吸烟。高于43°C时使用封闭系统、通风设备和防爆电气设备。
  • skin prevention: 防护手套。
  • Eye protection: Wear safety spectacles.
  • Target Organs: 眼睛,皮肤,呼吸系统,中枢神经系统
  • Toxicity Data: LCLo (大鼠) =3,484 ppm/8H
  • reactivity profile: 酮类,如乙基仲戊基酮,可与多种酸和碱反应,释放热量和可燃气体(例如 H2)。释放的热量可能足以在未反应的酮类部分引发火灾。酮类与还原剂(如氢化物、碱金属和氮化物)反应可产生可燃气体(H2)和热量。酮类与异氰酸酯、醛类、氰化物、过氧化物和酸酐不相容。它们与醛类、HNO3、HNO3 + H2O2 和 HClO4 剧烈反应。
  • reactive alarm: 高度易燃
  • Symptoms and Signs: 眼睛、皮肤、粘膜刺激;头痛;麻醉,昏迷;皮炎
  • Isolation and evacuation: 疏散:ERG2024, 指南 128 (乙基戊基甲酮): · 如果涉及储罐、铁路罐车或公路罐车起火,需在所有方向上隔离 800 米 (1/2 英里);同时,考虑在所有方向上初步疏散 800 米 (1/2 英里)。
  • DOT ID and Guide: 2271 128
  • Physical Dangers: 蒸气比空气重,可能沿地面扩散;远处可能被点燃。
  • Short-term exposure effects: 该物质对眼睛、皮肤和呼吸道有刺激性。该物质可能对中枢神经系统产生影响。暴露远高于职业接触限值(OEL)可能导致昏迷。
  • Air and water reaction: 易燃。不溶于水。
  • Hazard categories and classifications: 眼刺激 2
  • The impact of long-term exposure: 该物质会使皮肤脱脂,可能导致干燥或开裂。
  • Non-fire leakage response: 大量泄漏:在液体泄漏前方筑堤以便后续处置。水喷雾可减少蒸气,但在封闭空间中可能无法防止点燃。(ERG, 2024)
  • Personal protective equipment (PPE): 变更:未建议工人在工作班次后更换衣物。(NIOSH, 2024)
  • Protective Action Standards (PAC): PAC-3: 3000 [ppm]
  • DOT Hazard Classification: Placard/Label(s)
  • Respirator Recommendations: 关于呼吸器选择的重要补充信息
  • Accidental Release Measures: 泄漏或溢出:ERG2024,指南 128(乙基戊基酮):· 水雾可减少蒸气,但在封闭空间中可能无法防止点燃。
  • Threshold Limit Values (TLV): 10 ppm 作为时间加权平均值(TWA)。
  • Permissible Exposure Limit (PEL): TWA 25 ppm (130 mg/m3)
  • Recommended Exposure Limit (REL): TWA 25 ppm (130 mg/m3)
  • Occupational Exposure Limits (OEL): MAK (最大工作场所浓度): 53 mg/m
  • Emergency Response Planning Guidelines: 应急响应:ERG2024, 指南 128 (乙基戊基甲酮): · 对于大规模火灾,使用无人主水流设备或监控喷嘴;如果无法做到,撤离该区域并让火灾燃烧。
  • Exposure Control and Personal Protection: 最大允许浓度 (MAK): 10.0 [ppm]
  • Immediately Dangerous to Life or Health (IDLH): 参见:541855
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Research chemical >95. 0%; GC; 100ml

Research chemical >95. 0%; GC; 100ml; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: >95. 0%; GC; 100ml.

item number:M158857-100ml
Product model:100ml
level: >95. 0%; GC; 100ml
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