5-Methyl-4-nitroimidazole, an imidazole derivative, is a heterocyclic NH-acid. Its nitration in the presence of acetic anhydride/glacial acetic acid has been studied.5-Methyl-4-nitroimidazole may be used in the following: · To trap the reactive 1:1 intermediate formed during the reaction between triphenylphosphine and dibenzoylacetylene. · As a starting reagent in the synthesis of pyrazole derivatives. · Fabrication of zeolitic imidazolate frameworks (ZIFs). 5-Methyl-4-nitroimidazole, an imidazole derivative, is a heterocyclic NH-acid. Its nitration in the presence of acetic anhydride/glacial acetic acid has been studied.