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Product introduction

ML 145 是选择性，竞争性的人 GPR35/CXCR8 拮抗剂，IC50/EC50 为 20.1 nM。ML 145 对 GPR35 的选择性比 GPR55 (IC50/EC50=21.7 μM) 高超 1000 倍。 ML 145 对啮齿动物直系同源物的 GPR35 均无明显活性。 Product Describtion: ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. ML 145 has over 1000-fold more selective for GPR35 compared to GPR55 (IC50/EC50=21.7 μM)[1]. ML 145 has no significant activity for GPR35 at either rodent ortholog.

Specs ⸢ View details ⸥

Chinese name

ML 145,GPR35拮抗剂

English name

ML 145

Chinese alias

2-羟基-4-[4-(5-(Z))-5-[(E)-2-甲基-3-苯基丙-2-烯叉] -4-氧-2-磺基亚砜-1,3-噻唑烷-3-基]丁酰基氨基]苯甲酸

English alias

2-Hydroxy-4-[4-(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoic acid

CAS number

1164500-72-4

molecular formula

C24H22N2O5S2

molecular weight

482.57 g/mol

Exact mass

≥98%(HPLC)

PSA

164.000 Å²

Logp

5.100

Technical Documents

「No technical documents」

「No upstream and downstream information yet」

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ML 145, GPR35antagonist 100mg

Name: ML 145, GPR35antagonist 100mg
Brand: 阿拉丁
SKU: M287781-100mg

ML 145, GPR35antagonist 100mg; supplied for laboratory research, analysis, inspection, and scientific procurement use; specifications: 100mg; ≥98%; HPLC.

item number：M287781-100mg

Product model：100mg

level： 100mg; ≥98%; HPLC

Lead Time：30days

sold 382 Items

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Specifications：

100mg

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ML 145, GPR35antagonist 100mg

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