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Product introduction

甲氯环素是一种半合成的四环素，其通过将金霉素的6-羟基脱水以产生环外的6-亚甲基而制得。美洛西林是甲环素的紧密结构类似物。像所有四环素一样，甲氯环素显示出广谱的抗菌和抗原生动物活性，并通过与30S和50S核糖体亚基结合而起作用，从而阻止了蛋白质的合成。 Meclocycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of chlortetracycline to yield an exocyclic 6-methylene. Meclocyline is a close structural analogue of methacycline. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Specs ⸢ View details ⸥

Chinese name

甲环素

English name

Meclocycline

Chinese alias

甲氯环素

English alias

GS-2989 | 7-Chloro-6-methylene-5-oxytetracycline | Meclocyclinum

CAS number

2013-58-3

molecular formula

C22H21ClN2O8

molecular weight

476.86 g/mol

Exact mass

≥85%

PSA

182.000 Å²

Logp

0.9

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