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Product introduction

MHY1485 是一种有效的细胞渗透性 mTOR 激活剂，靶向 mTOR 的 ATP 结构域。MHY 1485 通过抑制自噬体和溶酶体之间的融合来抑制自噬 (autophagy)。 application： MHY1485 has been used: to study the effect of mammalian target of rapamycin mTOR signalling on in vitro O-GlcNAcylation to inhibit autophagy as a mTOR agonist to demonstrate that the O-linked N-acetylglucosamine transferase- RNA helicase p68 (OGT-DDX5) axis regulates colorectal cancer cell proliferation and metastasis

Specs ⸢ View details ⸥

Chinese name

4,6-二(4-吗啉基)-N-(4-硝基苯基)-1,3,5-三嗪-2-胺

English name

4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine

Chinese alias

4,6-二(4-吗啉基)-N-(4-硝基苯基)-1,3,5-三嗪-2-胺,4,6-二吗啉基-N-(4-硝基苯基)-1,3,5-三嗪-2-胺

English alias

MHY 1485 | 4,6-Di(4-morpholinyl)-N-(4-nitrophenyl)-1,3,5-triazin-2-amine | 4,6-dimorpholino-N-(4-nitrophenyl)-1,3,5-triazin-2-amine | MHY1485

CAS number

326914-06-1

molecular formula

C17H21N7O4

molecular weight

387.39 g/mol

Exact mass

≥98%

PSA

121.000 Å²

Logp

1.800

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