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Product introduction

ML-336 是一种喹唑啉酮类的委内瑞拉马脑炎病毒 (VEEV) 抑制剂，其VEEV TC-83 CPE(IC50:32 nM)、VEEV V3526 CPE(IC50:20 nM)、VEEV 野生型 CPE (IC50:42 nM)，有效抑制 VEEV 诱导的三种病毒株 (V3526、TC-83和野生型) 细胞病变效应。 Information ML336 is a potent inhibitor of the Venezuelan equine encephalitis virus (VEEV) strain TC-83. ML336 is quinazolinone-based inhibitor against venezuelan equine encephalitis virus (VEEV), with IC50s of 32, 20, and 42 nM for VEEV TC-83 CPE , VEEV V3526 CPE, VEEV Wild Type CPE, respectively. ML336 potently inhibits a VEEV-induced cytopathic effect in three strains of the virus (TC-83, V3526, and wild type Trinidad donkey) in the low nanomolar range.

Specs ⸢ View details ⸥

Chinese name

ML336

English name

ML336

Chinese alias

(E)-2-((1,4-二甲基哌嗪-2-亚基)氨基)-5-硝基-N-苯基苯甲酰胺

English alias

(E)-2-((1,4-dimethylpiperazin-2-ylidene)-amino)-5-nitro-n-phenylbenzamide

CAS number

1613465-33-0

molecular formula

C19H21N5O3

molecular weight

367.40 g/mol

Exact mass

≥95%

PSA

93.800 Å²

Logp

2.100

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