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Product introduction

M-31850 是一种有效，选择性和竞争性的 β-己糖胺酶 (β-hexosaminidase (Hex)) 抑制剂，对人 HexA 和 HexB 的 IC50 分别为 6.0 µM 和 3.1 µM。M-31850 还以 Ki 为 2.5 μM 来竞争性抑制 β-N-acetyl-D-hexosaminidase OfHex2。 M-31850 is a potent, selective and competitive β-hexosaminidase (Hex) inhibitor with IC50s of 6.0 µM and 3.1 µM for human HexA and human HexB, respectively. M-31850 also competitively inhibits β-N-acetyl-D-hexosaminidase OfHex2 with a Ki of 2.5 μM.

Specs ⸢ View details ⸥

Chinese name

M-31850

English name

M-31850

Chinese alias

2,2'-(氮杂二基双(乙烷-2,1-二基))双(1H-苯并[de]异喹啉-1,3(2H)-二酮)

English alias

2,2'-(Azanediylbis(ethane-2,1-diyl))bis(1H-benzo[de]isoquinoline-1,3(2H)-dione)

CAS number

281224-40-6

molecular formula

C28H21N3O4

molecular weight

463.48 g/mol

Exact mass

≥98%

PSA

86.800 Å²

Logp

3.600

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